Clinical value of glycosylated hemoglobin and homocysteine in nondiabetic elder patients with coronary heart disease

VernacularTitle:糖化血红蛋白和同型半胱氨酸在老年非糖尿病冠心病中的临床价值
Author: Huimin YUAN ; Jiangrong ZHANG ; Yan WANG
Publication Type:Journal Article
Keywords: Hemoglobin A,glycosylated/analysis; Cysteine/metabolism; Coronary disease; Aged
From: Journal of Chinese Physician 2013;15(11):1454-1457
CountryChina
Language:Chinese
Abstract: Objective To investigate hemoglobin A1c(HbA1c) and homocysteine (Hcy) in nondiabetic elder patients with coronary heart disease (CHD),and explore their clinical value.Methods Eighty-six non-diabetic elder patients with CHD [45 cases with acute coronary syndrome (ACS) and 41 cases with stable angina pectoris (SAP)] and sixty elder patients without diabetes mellitus and coronary heart disease as control group were selected.The plasma levels of HbA1c and Hcy in all groups were detected and analyzed.Results The levels of HbA1c and Hcy in CHD group were significantly higher than those in control group (P ＜0.05),and levels of HbA1c and Hcy in ACS group were both higher than SAP group (P＜0.05).The change of HbA1c and Hcy had positive correlation (r =0.34,P ＜0.05).Conclusions The levels of HbA1c and Hcy were higher in non-diabetic elder patients with CHD than those without CHD,and might correlate with atherosclerosis.HbA1c and Hcy might be markers of cardiovascular risk.