Quality Evaluation of Traditional Chinese Medicine by 1H-NMR-based Metabolomics
10.11842/wst.2013.09.001
- VernacularTitle:基于1H-NMR代谢组学技术的中药质量评价
- Author:
Gang FAN
;
Shanghua LUO
;
Yan LI
;
Er TAN
;
Yi ZHANG
- Publication Type:Journal Article
- Keywords:
Traditional Chinese medicine;
1H-NMR;
metabolomics;
species identification;
quality evaluation
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2013;(9):1862-1870
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine (TCM) is an important part of modern medicine. Application of modern ana-lytical techniques to identify the authenticity of TCM and evaluate its quality is an important and critical content in the process of the modernization and internationalization of TCM. This paper described the development and charac-teristics of a 1H-NMR-based metabolomics technology, and reviewed its application in the species identification, quality evaluation of Daodi Y aocai (i.e., genuine medicinal materials), processing theory and the best harvest time of TCM. Besides, based on previous work, further discussion was given on technical methods and key question of the 1H-NMR metabolomics method. This paper provided a methodological reference for the species identification and quality evaluation of TCM and other herbal medicines.