Applications of upconversion nanoparticles for cancer photodynamic therapy
10.3969/j.issn.1000-8179.20131767
- VernacularTitle:荧光上转换纳米材料在光动力学治疗癌症中的应用
- Author:
Xiaopeng ZHENG
;
Gan TIAN
;
Zhanjun GU
- Publication Type:Journal Article
- Keywords:
cancer;
up-conversion nanomaterial;
photodynamic therapy
- From:
Chinese Journal of Clinical Oncology
2014;(1):27-31
- CountryChina
- Language:Chinese
-
Abstract:
The advent of nanoscience and nanotechnology offers unprecedented opportunities in nanomedicine, such as increas-ing therapeutic efficiency and decreasing undesired side effects in cancer treatment. Photodynamic therapy (PDT) is a non-invasive pho-totherapy-based method that is applied in the treatment of cancer and other diseases and has important clinical value. PDT can be com-bined with other therapies to realize the synergistic treatment. The emergence of up-conversion nanomaterials provides a fundamental method to solve the problem of photodynamic therapy of deep tumors. Moreover, the versatile preparation and surface modification methods facilitate the fine-tuning of the emission spectrum of up-conversion nanomaterials and the improvement of the photosensitiz-er's loading capacity. This study reviews the development in design and application of up-conversion nanomaterials for PDT of cancer.
