Research on Formulation Process of Wuzibushen Capsules
10.3969/j.issn.1005-5304.2014.01.022
- VernacularTitle:五子补肾胶囊成型工艺研究
- Author:
Xuezheng LIANG
;
Yongchen TANG
;
Zhaoxuan WU
;
Hanshen ZHEN
;
Qin QIU
;
Xiaoyu HUANG
- Publication Type:Journal Article
- Keywords:
Wuzibushen capsules;
formulation process;
micromeritics;
critical relative humidity
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(1):71-73
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the forming process of Wuzibushen Capsules. Methods Category and ratio of accessories were investigated by taking moisture absorption percentage as index. The inspected angle of repose, bulk density and critical relative humidity were also investigated. Results Starch was used as the excipien. Remedium cardinale and starch in the ratio of 1.15∶1.25 was more appropriate, 60% alcohol was added, dried at 60 ℃. Granules had a good fluidity, critical relative humidity was about 62%. Conclusion The forming technology was reasonable and provide reliable basis for production.
