The clinical characteristics and resistance analysis of children infected with Klebsiella pneumonia in community and nosocomial
10.3969/j.issn.1671-8348.2013.36.008
- VernacularTitle:医院内感染和社区感染儿童肺炎克雷伯杆菌临床特点及耐药性分析
- Author:
Zuyuan HE
;
Zhimin CHEN
- Publication Type:Journal Article
- Keywords:
Klebsiella pneumonia;
beta-lactamase;
drug tolerance
- From:
Chongqing Medicine
2013;(36):4382-4384
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate clinical characteristics of children infected with Klebsiella pneumonia (KP) in community and nosocomial ,and analysis briefly about their resistance .Methods 79 cases of children with pneumonia identified as KP infection by the method of sputum bacterial culture were collected and divided into nosocomial infection group (11 cases) and community in-fection group(68 cases) from January 2009 to December 2012 .The clinical information were recorded ,sputum bacterial susceptibili-ty and extended-spectrum β-lactamase enzyme were tested .Results 10 cases and 12 cases of extended-spectrumβ-lactamase enzyme strains were detected from nosocomial infection group and community infection group ,respectively .The children infected KP had a high degree of resistance to cefazolin ,ampicillin/sulbactam ,head penicillin ,ceftriaxone ,aztreonam ,cefepime and ceftazidime ,while sensitive to ciprofloxacin ,cefotetan and piperacillin/tazobactam in the nosocomial infection group .12 cases in community infection group produce highly resistant to penicillin-type drugs ,but were not obvious resistance to other types of antibiotics .Conclusion Multi-drug resistance problems are serious in the pneumonia children who infected KP and the extended-spectrum β-lactamase en-zyme is positive .Infected children should be treated differently in the selection of antibiotics in the treatment of infection in commu-nity and nosocomial .
