Infant with incomplete Kawasaki disease present with sterile pyuria

VernacularTitle:以无菌性脓尿为首发症状的婴儿不完全性川崎病
Author: Hua HUANG ; Youyin MAO ; Lei YIN ; Wei ZHOU
Publication Type:Journal Article
Keywords: incomplete Kawasaki disease; sterile pyuria; infant
From: Journal of Clinical Pediatrics 2013;(12):1134-1137
CountryChina
Language:Chinese
Abstract: Objectives To explore the clinical features of incomplete Kawasaki disease (IKD) which presents with sterile pyuria in infant, in order to achieve early diagnosis and treatment. Methods A retrospective study of 15 infants with IKD was conducted in comparison with 29 patients who were diagnosed with KD according to the diagnostic criteria of American Heart Association 2004. Results Both KD and IKD groups had recurrent fever and poor response to antibiotic therapy. Hemoglobin level was signiifcantly lower in IKD group than in KD group at the onset or 7-d after onset (P<0.05). C-reaction protein (CRP) level was signiifcantly higher in IKD group than that in KD group at 7-d after onset (P<0.05). There were 4 patients with coronary artery abnormality, 2 patients with coronary artery dilation and 2 patients with coro-nary artery aneurysm. Conclusions For infant <1 year old who has pyuria ifrstly, continuous fever for over 5 days when treated by antibiotics and increasing serum inlfammatory markers, incomplete Kawasaki disease should be suspected and the cardiac ultrasound is recommended.