Clinical Study on Effect of Baohe Granules on Chronic Heart Failure Patients with TCM Syndrome and Gastrointestinal Hormone Secretion
10.11842/wst.2014.01.016
- VernacularTitle:保和颗粒对慢性心衰中医证候疗效及胃肠激素分泌影响的临床研究
- Author:
Linping ZHU
;
Xia LI
;
Limin FENG
;
Xuyan CAO
;
Yan LIU
;
Changyu LIU
;
Wuxun DU
;
Zongpei XU
- Publication Type:Journal Article
- Keywords:
Traditional Chinese medicine;
Baohe granules;
chronic heart failure;
gastrointestinal system;
therapeutic effect of TCM syndrome;
gastrointestinal hormone
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(1):87-92
- CountryChina
- Language:Chinese
-
Abstract:
This article was aimed to study the effect of Baohe granules for patients with chronic heart failure (CHF) of traditional Chinese medicine (TCM) syndrome and the effect of gastrointestinal hormone secretion. Patients with CHF were used as the object of study. A total of 80 selected patients were divided into 2 groups. The control group was treated with western medicine anti-heart failure therapy. The treatment group was treated with the combination of Baohe granules. All patients were compared in aspects of TCM efficacy, symptom score and serum gastrin, motilin secretion after two-week medication. The results showed that both treatments can significantly improve the TCM syn-drome and symptom total score of CHF patients. And the effect of the treatment group with Baohe granules was bet-ter. The TCM single symptom integral was also obviously improved in the treatment group combined with Baohe granules, which included heart palpitations, shortness of breath, abdominal distension, and loss of appetite. The GAS and MTL levels of CHF patients were significantly increased in the treatment group. It was concluded that the treat-ment combined with Baohe granules can improve CHF patients with TCM syndromes, symptoms and gastrointestinal hormone secretion. Thus, it contributed to the stability of the disease condition. It can slow the disease progression and improve prognosis. So it is worth using widely in the clinical practice.
