Some important issues in the translational medical research of radiofrequency ablation of liver cancer
10.3760/cma.j.issn.1007-8118.2013.11.002
- VernacularTitle:浅述肝癌射频消融转化医学研究的几个重要问题
- Author:
Wenbing SUN
- Publication Type:Journal Article
- Keywords:
Liver cancer;
Radiofrequency ablation;
Translational medicine
- From:
Chinese Journal of Hepatobiliary Surgery
2013;19(11):804-807
- CountryChina
- Language:Chinese
-
Abstract:
With increasing use of radiofrequency (RF) ablation in the treatment of liver cancer,more clinical problems are encountered.Translational research is urgently needed to solve these problems which include:(1) RF needle functional characteristics; (2) effects of RF ablation on liver cancer related changes in pathology; (3) changes in invasive ness and metastatic potential of residual liver cancer cells after incomplete ablation,and their mechanisms; (4) changes in tumor-associated endothelial cell function in residual liver cancer tissues after incomplete ablation,and their mechanisms; (5) prevention and treatment of residual liver cancer after RF ablation; (6) changes in the host's antitumor immunity after RF ablation of liver cancer.