Three-dimensional Quantitative Measurement of Spiral CT in Evaluating Tumor Size and T Stage of Stage I Non-small Cell Lung Cancer
10.3969/j.issn.1005-5185.2013.12.005
- VernacularTitle:螺旋CT三维定量测量评估I期非小细胞肺癌肿瘤大小及T分期的价值
- Author:
Jingxu LI
;
Yubao GUAN
;
Tingting XIA
;
Qiaohong ZHU
;
Shenshen SUN
;
Yan KANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Tomography,spiral computed;
Imaging,three-dimensional;
Neoplasm staging
- From:
Chinese Journal of Medical Imaging
2013;(12):899-902
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the value of three-dimensional quantitative measurement of spiral CT in evaluating tumor size and preoperative T stage in stage I non-small cell lung cancer (NSCLC). Materials and Methods The complete data of 125 patients with stage I NSCLC confirmed surgically and pathologically were compared in terms of maximum tumor diameter and T stage analysis by means of three-dimensional quantitative CT measurement, two-dimensional measurement and general pathology measurement. Results The mean maximum tumor diameter of these 125 patients measured by quantitative three-dimensional CT measurement, two-dimensional measurement and general pathology measurement were (26.21±8.14) mm, (27.03±9.90) mm and (25.60±9.31) mm, respectively. The difference in mean maximum tumor diameter by two-dimensional measurement and three-dimensional quantitative measurement was significant, and remained so when two-dimensional measurement and pathology measurement was compared (t=2.377, P<0.05;t=2.961, P<0.01), but that between three-dimensional quantitative measurement and pathology measurement was not significant (t=1.281, P>0.05). Bland-Altman analysis showed that three-dimensional quantitative measurement had higher consistency than two-dimensional measurement when compared with the gold standard pathology measurement. When three-dimensional quantitative measurement was taken to be the staging criterion, 20% results (25 cases) obtained by two-dimensional measurement proved to be inconsistent. Conclusion Compared with two-dimensional measurement, quantitative three-dimensional CT measurement can provide more accurate information in maximum tumor diameter and T stage for patients with stage I NSCLC, therefore can be applied as a more accurate criterion in preoperative staging and prognosis of stage I NSCLC.
