Evaluation of Carotid Artery Structure and Function of the Brachial Artery in Children with Coarctation of Aorta Using High-frequency Ultrasound
10.3969/j.issn.1005-5185.2013.11.007
- VernacularTitle:高频超声评价主动脉缩窄患儿颈动脉结构和肱动脉功能
- Author:
Hongying WANG
;
Jiemin ZENG
;
Xinxin CHEN
;
Jianru LI
- Publication Type:Journal Article
- Keywords:
Aortic coarctation;
Ultrasonography,Doppler,color;
Carotid arteries;
Brachial artery;
Vasodilation
- From:
Chinese Journal of Medical Imaging
2013;(11):821-824
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate the carotid artery structure and diastolic function of the brachial artery in children with coarctation of aorta (CoA) using high-frequency ultrasound. Materials and Methods Twenty-four cases of children with CoA were selected, among them seven cases were simple CoA and 17 cases were combined with other cardiac malformations, and 20 cases of simple ventricular septal defect (VSD) children and 20 healthy children over the same period were selected as the control groups. Carotid artery intima-media thickness (IMT) and brachial artery flow-mediated vasodilation (FMD) in all subjects were evaluated using high-frequency ultrasound, vascular structure and functional changes were compared before CoA correction and VSD repair treatment. Results Carotid artery IMT of CoA group was (0.47±0.12) mm, which was significantly larger than the VSD group (0.41±0.10) mm and the control group (0.40±0.09) mm, and the difference was statistically significant (F=4.275, P<0.05); brachial artery FMD [(5.48±1.66)%] of CoA group was significantly lower than that of the VSD group [(6.69± 1.45)%] and the control group [(6.59±1.84)%], and the difference was also statistically significant (F=4.318, P<0.05), but there was no significant difference (q=0.400, 0.191;P>0.05) between the VSD group and the control group for carotid artery IMT and brachial artery FMD. Conclusion In children with CoA, besides the structure abnormalities of the narrowing vascular, there is also the combination of structural and fuctional changes such as carotid artery intima-media complex thickening and brachial artery flow-mediated dilation function decrease.
