Effects of Different Production Techniques of Shuxue Tongmai Capsules on Mouse Blood Coagulation Function and Thrombosis Formation

VernacularTitle:不同工艺疏血通脉胶囊对小鼠凝血功能及血栓形成的影响
Author: Tai LIU ; Jun ZHOU ; Qiuhong LIN ; Yuying HU ; Bin CAO ; Wei GAO ; Yuqiang WU ; Li WANG ; Ying LIU ; Qingping ZHANG ; Qianchao HE
Publication Type:Journal Article
Keywords: Shuxue Tongmai capsules; clotting time; bleeding time; collagen-adrenaline model of mice
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(8):1792-1795
CountryChina
Language:Chinese
Abstract: This study was aimed to evaluate effects of different production techniques of Shuxue Tongmai (SXTM) capsules for blood coagulation function and thrombosis formation among mice. The observation was made on the clot-ting time, bleeding time and instauration rate of collagen-adrenaline model of mice. The results showed that com-pared with SXTM II and Ⅲ production technique, the SXTM I production technique of the same dosage group can prolong the clotting time of mice significantly (P < 0.05), and increase the instauration rate of collagen-adrenaline model of mice significantly (P< 0.05). There was no significant difference on the bleeding time of mice between the SXTM I production technique of same dosage group and the saline group. It was concluded that the SXTM had an-ticoagulative and antithrombotic effects. And the SXTM I production technique receives better effects.