Differential Diagnosis of Chromophobic Renal Cell Carcinoma and Renal Oncocytoma:Dynamic Contrast-Enhanced CT Analysis
10.3969/j.issn.1005-5185.2013.10.012
- VernacularTitle:CT动态增强扫描鉴别肾嫌色细胞癌与肾嗜酸细胞瘤的价值
- Author:
Xiaojing KONG
;
Haiyi WANG
;
Huiyi YE
- Publication Type:Journal Article
- Keywords:
Carcinoma,renal cell;
Adenoma,oxyphilic;
Tomography,spiral computed;
Image enhancement;
Diagnosis,differential
- From:
Chinese Journal of Medical Imaging
2013;(10):761-764
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To explore the diagnostic value of dynamic contrast-enhanced CT (DCE-CT) in the differential diagnosis of chromophobic renal cell carcinoma (CRCC) and renal oncocytoma (RO). Materials and Methods A retrospective study was carried out on the DCE-CT findings of 24 patients with pathologically-proved CRCCs and 17 patients with pathologically-confirmed ROs. The enhancement percentage (EP) and the enhancement index (EI) of both types of lesions were compared on corticomedullary phase and nephrographic phase. Results CRCCs on corticomedullary phase and nephrographic phase:EP (132.8±39.8)%and (99.2±32.5)%, respectively;EI 0.31±0.11 and 0.30±0.12, respectively. ROs on corticomedullary phase and nephrographic phase:EP (234.1±129.1)%and (195.4±87.1)%, respectively;EI 0.66±0.33 and 0.68±0.28, respectively. Both EP and EI of CRCCs and ROs showed statistical difference (P<0.05). As the threshold value of EI on nephrograhic phase was 0.44, the sensitivity was 82.4%, specificity was 91.7% and Youden index was 0.74. Conclusion Imaging features of DCE-CT, especially EI on nephrographic phase, are helpful in the differential diagnosis of CRCC and RO.
