Study on Extraction Techniques of Compound Rhubarb Enema by Multi-index Comprehensive Evaluation

VernacularTitle:多指标综合评价复方大黄灌肠液提取工艺研究
Author: Minyang GONG ; Xiaoyan WU ; Suhong QIN ; Chao CHEN ; Quanfang HUANG
Publication Type:Journal Article
Keywords: Compound Rhubarb Enema; analytic hierarchy process; multi-index comprehensive evaluation; extraction techniques; orthogonal test
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(8):1825-1830
CountryChina
Language:Chinese
Abstract: This study was aimed to optimize extraction techniques of Compound Rhubarb Enema. Based on the for-mula principle of Compound Rhubarb Enema, effects of the amount of water, soaking time, extraction time and fre-quency on each index were studied. The content of Aloe-emodin, Rhein, Emodin, Chrysophanol, Physcion, Citric acid, and water soluble substance were taken into consideration. The best extraction condition was optimized by using the orthogonal test coupled with the multi-index comprehensive evaluation. The results showed that the best condi-tion was soaking for 10 min, extraction time for 60 min, extraction for 3 times; and 6 times of water was added. It was concluded that this preparation techniques were feasible and reliable for the manufacturing process of Compound Rhubarb Enema.