RIFLE and AKIN criteria for mortality and risk factors of acute kidney injury in hospitalized patients
10.3969/j.issn.1672-7347.2013.12.007
- VernacularTitle:RIFLE和AKIN标准在评价住院急性肾损伤患者病死率及其相关危险因素中的应用
- Author:
Shaobin DUAN
;
Qing LIU
;
Peng PAN
;
Jun XU
;
Na LIU
;
Ying LI
;
Hong LIU
;
Youming PENG
;
Lin SUN
;
Fuyou LIU
- Publication Type:Journal Article
- Keywords:
acute kidney injury;
renal failure;
RIFLE;
AKIN;
risk factors;
mortality
- From:
Journal of Central South University(Medical Sciences)
2013;38(12):1243-1252
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the mortality and risk factors for acute kidney injury (AKI) in hospitalized patients by the risk, injury, failure, loss, end stage kidney disease (RIFLE) and acute kidney injury network (AKIN).
Methods:We constructed a retrospective study of all AKI patients in the Second Xiangya Hospital of Central South University between February 2006 and January 2011. The diagnosis and classiifcation of AKI were reconifrmed and categorized by RIFLE and AKIN criteria. To compare the clinical characteristics, mortality and associated risk factors in AKI patients by the RIFLE and AKIN stage, univariate analysis and multivariate logistic regression analysis were performed. Results:The patients were diagnosed as AKI by AKIN (n=1027) or by RIFLE criteria (n=1020). There was no signiifcant difference in the hospital mortality, hospital length stay (days), or the proportion of complete recovery in each stage of AKI patients by RIFLE and AKIN (P>0.05). In the univariate analysis, age, pre-renal causes, proportion of hospital acquired AKI, mechanical ventilation, hypotension, the number of failed organs, acute tubular necrosis-index severity score (ATN-ISS), and the peak of serum potassium ion concentration were signiifcantly higher in the non-survivors than in the survivors (P<0.05). Logistic regression analysis revealed that age older than 65, hospital acquired AKI, hypotension, number of failed organs, ATN-ISS scores, and the peak of serum potassium ion concentration were independent risk factors for hospital mortality. Conclusion:Both RIFLE and AKIN criteria have similar scientiifc value in assessing hospital mortality. AKI stage is associated with the recent prognosis of AKI patients.
