A systematic review for donor kidneys after resection of small renal cancer

VernacularTitle:小肾癌肾脏作为供肾应用于临床肾移植的荟萃分析
Author: Nengwang YU ; Shuai FU ; Xiaofei WANG ; Junwen HAO ; Aimin ZHANG ; Xiangtie LI
Publication Type:Journal Article
Keywords: Kidney transplant; Renal cancer; Donor; Systematic review
From: Chinese Journal of Organ Transplantation 2013;34(12):733-736
CountryChina
Language:Chinese
Abstract: Objective To review the literature and synthesize current evidence on the use of kidneys with small renal cancer as donor kidneys.Method To locate eligible studies,four bibliographic databases including PubMed,Embase,Cochrane Library and ClinicalTrials.gov were screened,while key informants were collected and bibliographies of included studies were scrutinised.Two reviewers independently assessed studies for inclusion,extracted data.Data were synthesised as a narrative review.Results 1680 articles were found while eventually 15 studies were selected for this systematic review.All of the 15 included studies were case reports or case series.Totally 96 documented cases of donor kidneys after resection of small renal cancer were transplanted and no definite recurrence happened.Conclusion It is suggested from current limited evidence that cancer recurrence rate of allotransplanting kidney after resection of SRC was relatively low,thus it deserved much more well-designed clinical trials and clinical use.