Advance of the nucleic acid techniques in the breast cancer diagnostics
10.3760/cma.j.issn.1009-9158.2013.11.004
- VernacularTitle:核酸技术在乳腺癌实验诊断中的进展
- Author:
Fubing WANG
;
Jiancheng TU
- Publication Type:Journal Article
- Keywords:
Breast cancer;
Circulating DNA/miRNAs;
Aptamers;
Circulating tumor cells
- From:
Chinese Journal of Laboratory Medicine
2013;36(11):978-982
- CountryChina
- Language:Chinese
-
Abstract:
Traditional immunological strategy which largely based on antigen-antibody techniques such as CA153,cytokeratin CK8/18/19,is still the main diagnostic biomarkers for breast cancer.Molecular biology markers such as BRCA1/2 and HER2 are becoming popular and hot.This article summarizes recent progress of breast cancer diagnosis based on nucleic acid related strategies such as circulating DNA,miRNAs,aptamers and circulating tumor cells.