The diagnosis, treatment and prognosis of colorectal small cell carcinoma: an analysis of 15 cases
10.3760/cma.j.issn.1007-631X.2013.12.019
- VernacularTitle:结直肠小细胞癌临床病理特征与预后分析
- Author:
Shuai HUANG
;
Zhaoxu ZHENG
;
Quan XU
;
Xinghua YUAN
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Carcinoma,small cell;
Pathology,clinical;
Prognosis
- From:
Chinese Journal of General Surgery
2013;28(12):961-964
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize and analyze the clinical feature,therapeutic mnethods and prognosis of colorectal small cell carcinoma.Methods From January 2000 to January 2012,15 patients of colorectal small cell carcinoma were analyzed retrospectively.Results There were 12 male cases,3 females.The age at diagnosis was between 39-71 years,with median age of 60.SCC located in the rectum in 12 cases,in the colon in 3 cases.The time from the onset of symptoms to final diagnosis was from 1 to 12 months.The diameter of tumors varied from 2.5 to 8.0 cm.13 cases received up-front surgery,including radical tumor resection in 6 cases,palliative resection in 7 cases,and neoadjuvant-chemotherapy followed by palliative resection in one case.The initial Ⅰ,Ⅲ B,Ⅳ B stage were 1 case,6 cases and 8 cases,respectively.The overall median survival time is 11 months,1,2 year's survival rate is 40.0％ and 20.0％,respectively.Conclusions Colorectal SCC is less common and the prognosis is poor.Multimodality management,with radical surgical resection of the primary lesion followed by standard adjuvantchemotherapy,affords good local disease control and a fair survival.
