Effect of low-dose radiation on ocular lens of radiation workers: Meta-analysis

VernacularTitle:低剂量电离辐射对放射工作人员眼晶状体影响的Meta分析
Author: Jing JIANG ; Ting KONG ; Bo HUANG ; Pingkun ZHOU ; Weiqing RANG
Publication Type:Journal Article
Keywords: Radiation workers; Ionizing radiation; Lens opacity; Meta-analysis
From: Chinese Journal of Radiological Medicine and Protection 2013;33(6):640-644
CountryChina
Language:Chinese
Abstract: Objective To comprehensively analyze the effect of low-dose radiation on the lens of the eye of radiation workers.Methods The papers dealing with the relationship between occupational radiation exposure and the lens of the eye were collected by retrieving documents of the domestic and foreign medical information databases with references to other papers.There were 28 papers finalized with 17 608 workers included in the Meta-analysis.Stata12.0 was used for Meta-analysis,Q-test and I2 statistic for heterogeneity test,and funnel regression method,Begg's rank method and Egger's regression method for publication bias.Results The pooling odds ratio (OR) opacity in radiation workers were 2.51 (2.01,3.13),4.03 (2.77,5.85),respectively.Conclusions Low-dose radiation may lead to negative impact on ocular lens under the current occupational protection conditions.The proportion of posterior subcapsular opacity in radiation-related cataract is higher than that in age-related cataract.It is important to strengthen radiation protection of ocular lens.