Value of three-dimensional power Doppler ultrasound in diagnosis of cervical cancers

VernacularTitle:三维能量多普勒超声对宫颈癌的诊断价值
Author: Wei LIU ; Litao SUN ; Nana LIU ; Zhenzhen WANG ; Xinying DOU ; Xianchao KONG
Publication Type:Journal Article
Keywords: Ultrasonography; Uterine cervical neoplasms
From: Chinese Journal of Ultrasonography 2013;22(12):1056-1059
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical value of three-dimensional power Doppler ultrasound (3D PDUS) in diagnosing cervical cancers.Methods 162 patients with cervical lesions were enrolled.All the cases were confirmed by autopsy or surgery.Vascularization index (VI),flow index (FI) and vascularization flow index(VFI) were all measured and compared.The pathological findings was taken as golden standard.ROC curve was used to find the best cut-off value.Results 3D PDUS indices of benign and malignant lesions were statistically different (P ＜0.0001).The best cut-off value of VI was 4.63 using ROC curves,the area under the curve (AUC) was 0.94,the sensitivity and specificity were 89.10％ and 86.30％,respectively.The best cut-off value of FI was 34.39 using ROC curves,AUC was 0.76,the sensitivity and specificity were 73.40％ and 76.70％,respectively.The best cut-off value of VFI was 1.60 using ROC curves,AUC was 0.93,the sensitivity and specificity were 87.50 ％ and 86.30 ％,respectively.Conclusions 3D PDUS was a new and noninvasive way for the clinical to differentiate benign and malignant cervical lesions.