Clinical research of sentinel lymph node imaging for contrast-enhanced ultrasonography in colorectal cancer during operation
10.3760/cma.j.issn.1004-4477.2013.11.014
- VernacularTitle:超声造影在结直肠癌术中前哨淋巴结显像中的应用研究
- Author:
Ting YAN
;
Wen WANG
;
Hai LI
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Colorectal neoplasms;
Sentinel lymph node
- From:Chinese Journal of Ultrasonography
2013;22(11):962-964
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the feasibility of contrast-enhanced ultrasonography (CEUS) in detecting sentinel lymph node(SLN) in patients with colorectal cancer during operation and their clinical significance.Methods Twenty-one patients who underwent radical resection of a primary colorectal cancer were enrolled.During operation,1 ％ methylene blue was injected around the tumor,SLN mapping was performed.Then the SonoVue was injected at the same sites,CEUS was performed to observe changes of SLN in real time,and marked them.The SLN detection rate and accuracy of CEUS were compared to those of conventional dye guided method.Results The rectal cancer of below peritoneal reflex,the detection rate of CEUS for SLN was 92.31 ％,and the accuracy was 88.89％.The detection rate of dye guided method for SLN was 84.62％,and the accuracy was 93.10％,there was no statistically significant difference between CEUS and dye guided method (P ＞0.05).Conclusions When injected SonoVue in submucosal layer,the good mapping of SLN of patients with rectal cancer of below peritoneal reflex can be obtained,it will play an important role in clinical application to map SLN of patients with rectal cancer of below peritoneal reflex.
