Long term prognosis and risk factors of percutaneous microwave ablation treatment of recurrence hepatocellular carcinoma after hepatectomy
10.3760/cma.j.issn.1004-4477.2013.11.012
- VernacularTitle:经皮微波消融治疗术后复发性肝癌的长期生存影响因素分析
- Author:
Tingting ZHANG
;
Kaiyan LI
;
Wei ZHANG
;
Liying ZHANG
;
Meng GAO
;
Youbin DENG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Carcinoma,hepatocellular;
Neoplasm recurrence,local;
Microwaves/therapeutic use;
Survival rate
- From:
Chinese Journal of Ultrasonography
2013;22(11):957-961
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic results of percutaneous microwave ablation for patients with recurrence primary liver cancer after surgery and the factors influencing the survival after ablation therapy.Methods 102 patients who underwent hepatectomy for primary liver cancer in April 1998 to December 2010,and subsequent microwave ablation for recurrence hepatocellular carcinoma,were enrolled.Long term survival rates and prognostic factors after ablation were analyzed.Results The 1,3,5,and 7 year overall survival rates after ablation were 73.5％,53.5％,40.5％ and 17.7％.The 1,3,and 5 year overall survival rates for patients within one year recurrence after hepatectomy were 63.3％,38.9％,and 27.1％,respectively,which was significantly lower than that for patients after this time period in which the 1,3,and 5 year overall survival rates were 86.3％,72.3％ and 63.0％,respectively (P =0.003).Univariate analysis revealed that recurrence tumor size more than 3 cm,multiple tumors,poor Child-Pugh score,and AFP level ＞100 μg/L were risk prognostic factors of overall survival for patients who underwent ablation.Multivariate analysis identified multiple tumors,poor Child-Pugh score,and AFP level ＞ 100μg/L were the factors affecting overall survival.Conclusions Microwave ablation is of high clinical application value and is an effective minimally invasive treatment for recurrence hepatocellular carcinoma.Microwave ablation is equally effective when used in late recurrence,single tumor and tumor size≤3 cm.
