Evaluation of the security of catheter-based renal denervation by two dimensional speckle tracking imaging
10.3760/cma.j.issn.1004-4477.2013.11.025
- VernacularTitle:二维斑点追踪技术评价射频消融肾交感神经的安全性
- Author:
Wei HU
;
Ruiqiang GUO
;
Shengbo YU
;
Jinping XIAO
;
Xule WANG
;
Zixuan DAI
;
Qingyan ZHAO
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Kidney;
Sympathetic nerve;
Catheter ablation;
Ventricular function,left
- From:
Chinese Journal of Ultrasonography
2013;22(11):997-1000
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the security of catheter-based renal denervation by two dimensional speckle tracking imaging.Methods 20 dogs was ablated,whose indicies of heart and blood pressure were detected 6 weeks later.Standard 2D images were acquired in the 2-,3-and 4-apical views as well as the parasternal short-axis views at the level of the mitral valve and papillary muscles.The time to peak-systolic strain of each segment in the level of the mitral valve and papillary muscles,the standard deviation of the time to peak-systolic strain,the peak strain of the longitudinal 12-segment were recorded.Parameters were compared among the before and after ablation.Results Compared with before ablation of renal sympathetic nerve,the systolic pressure and diastolic pressure didn't reduced significantly after the ablation of renal sympathetic nerve (P > 0.05),while there were no significant difference in the peak strain of the longitudinal 12-segment,the dyssychrony parameters and the size of the heart cavity before and after ablation(P >0.05).Conclusions The pressure had no change after the ablation of renal sympathetic nerve while without harmful effect on the the size of the heart cavity,the function of the myocardial contraction and the dyssychrony parameters.The ablation of renal sympathetic nerve can' t lower the normal blood pressure and be safe for heart at the same time.