Impact of nutrition support on clinical outcomes for the patients with gastrointestinal disease at nutritional risk by Nutrition Risk Screening 2002 tool and the preliminary finding of cost-effectiveness analysis: a prospective cohort study for 275 patien
10.3760/cma.j.issn.1674-635X.2013.06.002
- VernacularTitle:营养支持对有营养风险胃肠病患者临床结局的影响以及成本-效果比初步探讨:275例前瞻性队列研究
- Author:
Yan WANG
;
Zhuming JIANG
;
Kondrup JENS
;
Yang WANG
;
Nolan MARIE
;
Jiaming QIAN
;
Kang YU
- Publication Type:Journal Article
- Keywords:
Nutritional risk;
Malnutrition (undernutrition);
Nutrition support;
Cost effectiveness ratio;
Gastrointestinal disease;
Incremental cost effectiveness ratio
- From:
Chinese Journal of Clinical Nutrition
2013;21(6):333-338
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the impact of nutrition support on the clinical outcomes of gastrointestinal disease patients at nutritional risk and explore the the cost-effectiveness of various nutrition support options.Methods A prospective cohort study was designed.The patients who met the predetermined inclusion criteria were followed up during the hospital stay.Nutritional risk was determined using the Nutrition Risk Screening 2002 on admission.The information with respect to nutritional support,occurrence and treatment of complications,length of hospital stay,and discharge destination was monitored and recorded.The direct costs of nutritional support and the costs of diagnosing and treating complications were calculated after discharge.Infectious complication-free patient was used as the effectiveness indicator in the cost-effectiveness analysis.Results Patients who had received nutrition support had significantly lower infectious complications incidence (6.8% vs.19.6%,x2 =9.0,P=0.003) and significantly higher total hospitalization costs (P =0.0001).The adjusted (by general linear model) cost of parenteral nutrition (PN) cohort,enteral nutrition (EN) cohort,PN combined EN cohort,and the cohort without nutritional support were 5635,1212,5220,and 1339 China Yuan,respectively.The incremental cost effectiveness ratios were 36 101,-794,and 33 748 China Yuan for PN,EN,and PN-EN combination groups,respectively.Conclusions For the patients at nutritional risk,nutritional support can remarkably reduce the incidence of infectious complications.The preliminary resuits of cost-effectiveness:due to lack of enough data required by health economic professional,it can not be cited directly.