Antitumor mechanism of kaempferol
10.3760/cma.j.issn.1673-422X.2013.12.004
- VernacularTitle:山奈酚的抗肿瘤作用
- Author:
Chengrui FU
;
Baosheng LI
- Publication Type:Journal Article
- Keywords:
Kaempferols;
Neoplasms;
Apoptosis;
Cell cycle
- From:
Journal of International Oncology
2013;40(12):892-895
- CountryChina
- Language:Chinese
-
Abstract:
Kaempferol is a kind of flavonoid compound that exists in natural plants including fruits,vegetables and Chinese herbal medicine.Kaempferol has extensive pharmacological activities,including antitumor,antioxidant,anti-inflammatory,anxiolytic,analgesic and antiallergic activities.Researches show that Kaempferol can reduce the risk of cancer,can inhibit proliferation and invasion of tumor cells by inducing apoptosis,regulating cell cycle,inhibiting angiogenesis and tumor metastasis.Meanwhile,kaempferol can suppress tumor growth by regulating the oxidative stress reaction and inhibiting inflammatory cytokines.In a word,kaempferol has broad prospects in cancer prevention and treatment.
