Fine-needle aspiration combined with molecular biomarkers in the diagnosis of thyroid nodules
10.3760/cma.j.issn.1673-422X.2013.11.011
- VernacularTitle:细针穿刺联合分子生物标志物在甲状腺结节诊断中的研究进展
- Author:
Chuanxin XIE
;
Shengying WANG
- Publication Type:Journal Article
- Keywords:
Thyroid nodule;
Biological markers;
Biopsy,needle
- From:
Journal of International Oncology
2013;40(11):836-839
- CountryChina
- Language:Chinese
-
Abstract:
The check methods of thyroid nodules include palpation,serum thyroid hormone and high-frequency ultrasound.When the diagnosis is difficult,fine-needle aspiration (FNA) is carried to differentiate benign and malignant nodules.In clinical practice,approximately 20% of FNA-derived cytology reports can not meet the standard of benign or malignant.Some specific molecular biomarkers are applied to the derivative detection of FNA,which achieve considerable progress and improve the preoperative diagnostic rate.