Clinical trials of receptor protein-tyrosine kinase inhabitors in malignant glioma
10.3760/cma.j.issn.1673-422X.2013.11.010
- VernacularTitle:受体酪氨酸激酶抑制剂在恶性胶质瘤中的临床试验进展
- Author:
Hao ZHU
;
Jinfang XU
;
Hong SHEN
- Publication Type:Journal Article
- Keywords:
Glioma;
Clinical trial;
Receptor protein-tyrosine kinase inhabitor
- From:
Journal of International Oncology
2013;40(11):833-836
- CountryChina
- Language:Chinese
-
Abstract:
The occurrence and development of malignant glioma are closely related to abnormal overexpression and activation of receptor tyrosine kinase (RTK) signal transduction pathways.Targeted therapeutic drugs such as RTK inhibitors,RTK downstream signaling pathway inhibitors and multi-target inhibitors can targeting treat malignant glioma at molecular level,some of which have been investigated in clinical trials and achieved good therapeutic effects.
