Neurobiology of head-neck squamous cell carcinoma
10.3760/cma.j.issn.1673-422X.2013.11.009
- VernacularTitle:头颈鳞状细胞癌的神经生物学
- Author:
Rong YANG
;
Wei LU
;
Tong JI
- Publication Type:Journal Article
- Keywords:
Carcinoma,squamous cell;
Neoplasm metastasis;
Neurotrophic factors;
Neurogenesis
- From:
Journal of International Oncology
2013;40(11):830-833
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal nerves exist in tumor tissues,and tumor cells can invade nerve by neurogenesis.Current research shows that cancer cells can secrete cytokines to promote the differentiation and growth of nerve cells,in turn,the differentiation and growth of nerve cells can stimulate tumor development and metastasis.Neurogenesis is one way of interaction bettween tumor cells and microenvironment similar to angiogenesis and lymphangiogcnesis,which has a major impact on biological behavior of tumor cells and prognosis.
