Research progress of tissue-engineered oral mucosa
10.3760/cma.j.issn.1673-4181.2013.06.013
- VernacularTitle:组织工程化口腔黏膜研究进展
- Author:
Linpu ZHANG
- Publication Type:Journal Article
- Keywords:
Oral mucosa;
Tissue engineering;
Transplantation;
Model;
Squamous cell carcinoma
- From:
International Journal of Biomedical Engineering
2013;36(6):371-375
- CountryChina
- Language:Chinese
-
Abstract:
Large area defect of intra-oral or extra-oral mucosa caused by mucosa lesions need suitable graft materials for repair.Tissue engineering methods can provide effective pathway to resolve this problem.Furthermore,full thickness mucosa equivalent constructed by tissue engineering methods also can be used as a model to evaluate dental materials,drug delivery system and oral carcinogenesis.Basic issues of tissue-engineered mucosa including sources of seed cells,scaffold materials such as de-epidermised acellular dermis,collagens,fibrin glue and biomacromolecule electrostatic spinning are discussed in this review,and the application researches of tissueengineered mucosa for mucosa reconstruction and mucosa model equivalents are expounded too.
