The clinical characteristics and cognitive function of Parkinson's disease patients associated with pain

VernacularTitle:帕金森病伴疼痛患者临床特征及认知功能研究
Author: Xiaoyi ZHANG ; Chengjie MAO ; Yi CHEN ; Weidong HU ; Jie LI ; Chunfeng LIU
Publication Type:Journal Article
Keywords: Parkinson disease; Pain; Cognition
From: Chinese Journal of Internal Medicine 2014;53(1):27-30
CountryChina
Language:Chinese
Abstract: Objective To explore the type and etiology of chronic pain in patients with Parkinson's disease (PD),and to assess the association between pain and cognitive function.Methods A total of 116 PD patients were enrolled in the study and assessed with the following rating scales:Unified Parkinson's Disease Rating Scale (UPDRS),Hoehn-Yahr Scale (H-Y),Hamilton Depression Rating Scale for Depression(HRSD),Visual Analogue Scale (VAS) and Montreal Cognitive Assessment (MoCA).Results Compared with PD patients without pain,PD patients with pain had higher scores of UPDRS,H-Y and HRSD rating scales.Depression(scores of HRSD) was the only factor associated with pain showed by the Logistic regression model (P =0.007).PD patients with pain had lower scores of delayed recall (P =0.020).PD patients with pain happened before their motor symptoms had a lower score of delayed recall (P =0.015).Conclusions Musculoskeletal pain is the most common type in PD patients with pain.Depression is probably an independent risk factor for pain in PD patients.Delayed recall is the dominant impaired cognitive function.