MicroRNA and renal carcinoma
10.3760/cma.j.issn.1673-422X.2013.07.019
- VernacularTitle:微小RNA与肾癌
- Author:
Xuyi MA
;
Haiyan XU
;
Xiaozhou HE
;
Xueguang ZHANG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Kidney neoplasms;
Oncogenes;
Genes,tumor suppressor
- From:
Journal of International Oncology
2013;40(7):536-539
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are evolutionary conserved non-coding RNA molecules.They involve in a variety of biological processes such as regulating the individual development,cell division,differentiation,apoptotic and fat metabolism through post-transcription pathway.It has been shown that miRNAs play important roles in the development and progression of many tumors,including of renal carcinoma,miRNAs play functions similar to oncogenes or anti-oncogenes in the development and progression of renal carcinoma by regulating the signaling pathway of its target genes involving in.