Epidemiological Characteristics of Adverse Reaction Induced by Chinese Activating Blood Herbal Injection

VernacularTitle:活血类中药注射剂不良反应流行病学特点研究
Author: Jiarui WU ; Libiao MA ; Bing ZHANG ; Xiaomeng ZHANG
Publication Type:Journal Article
Keywords: Chinese activating blood herbal injection; drug adverse reaction; drug epidemiology
From: Chinese Journal of Information on Traditional Chinese Medicine 2013;(7):24-26
CountryChina
Language:Chinese
Abstract: Objective To investigate the epidemiological characteristics of adverse reaction induced by Chinese activating blood herbal injection. Methods Domestic medicinal periodicals issued during 1972-2011 were searched, and 566 adverse drug reaction (ADR) cases were analyzed by database establishment and statistic method. Results Totally 566 ADR cases involving 16 different kinds of traditional Chinese medicine injection were collected, and 139 cases were related to Fufang Danshen Injection. The incidence of ADR was 51.77%(293 cases) in the male and 48.23%(273 cases) in the female. Average age of patients was (55.01±16.07) years old. The incidence of circulation system damage (206 cases, 23.22%) dominated in ADRs. The number of ADR which occurred within half an hour was 357 cases (64.79%) and the original disease most were cardiovascular and cerebrovascular diseases (384 cases, 67.84%). Conclusion ADR induced by Chinese activating blood herbal injection are commonly seen in middle-aged and elderly people, and often involved circulation system.