Clinical application of 4 serum tumor markers in primary gastric lymphoma

VernacularTitle:4种血清肿瘤标志物在原发性胃淋巴瘤的临床应用研究
Author: Hong HUANG ; Qin MAO ; Shenglin QUAN ; Tianrui YAN
Publication Type:Journal Article
Keywords: lymphoma; carbohydrate antigen 125; lactic dehydrogenase; β2-microglobulin; serum ferritin
From: Chongqing Medicine 2013;(26):3117-3119
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical significance of quantitatively detecting serum cancer antigen 125(CA125) ,lactate dehydrogenase(LDH) ,β2-microglobulin(β2-MG) and serum ferritin(SF) in primary gastric lymphoma(PGL) .Methods The clini-cal data in 41 cases of PGL confirmed by Pathological examination were retrospectively analyzed on the serum CA 125 ,LDH ,β2-MG and SF levels ,and their relationship with the pathological type ,clinical phase ,grouping ,international prognostic index (IPI) andHe-licobacter pylori infection were compared .Results The serum levels of CA125 ,LDH ,β2-MG and SF in the Ⅲ + Ⅳ stage were high-er than those in the Ⅰ + Ⅱ stage in PGL patients(P<0 .05);the IPI scores in the middle-higher risk + high risk group were obvi-ously higher than those in the lower risk + low-middle risk group (P<0 .01) .There were no significant differences in the patho-logical type ,grouping and Helicobacter pylori infection .Conclusion Detecting the levels of CA125 ,LDH ,β2-MG and SF has the im-portant clinical value to the clinical phase and the prognostic judgment in PGL .