Qingrehuashi Herbal Formula combined with high intensity focused ultrasound for treating advanced pancreatic cancer
10.3969/j.issn.1671-8348.2013.27.010
- VernacularTitle:清热化湿中药联合高强度聚焦超声治疗晚期胰腺癌的临床分析
- Author:
Kun WANG
;
Huifeng GAO
;
Zhiqiang MENG
;
Zhen CHEN
;
Junhua LIN
;
Peng WANG
;
Lanyun FENG
;
Yehua SHEN
;
Lianyu CHEN
;
Weidong SHI
;
Luming LIU
- Publication Type:Journal Article
- Keywords:
Ultrasonics;
drugs,Chinese herbal;
pancreatic neoplasms
- From:
Chongqing Medicine
2013;(27):3231-3233
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of Qingrehuashi herbal formula combined with high intensity focused ul-trasound(HIFU ) in the treatment of advanced pancreatic cancer .Methods 86 patients with pancreatic cancer (22 case of III stage and 64 case of IV stage) were included in this study .18 cases were performed the HIFU therapy for 2-3 times .Other 68 cases re-ceived once HIFU therapy ,among 53 cases of liver metastasis ,8 cases were simultaneously conducted HIFU ablation therapy on liv-er metastasis .The patients were given Chinese medicines dominated by Qingrehuashi before and after HIFU therapy and during fol-low up period .Results The single evaluation on HIFU irradiation cases after 1 month:complete remision(CR) in 0 case ,partial re-mission(PR) in 8 cases(9 .3% ) ,stable disease(SD in 64 cases(74 .4% ) and progress disease(PD) in 14 cases(16 .3% ) .The median survival rate of 1 year and half a year was 52 .0% and 11 .4% .Among 73 cases of increased CA199 before treatment ,CA199 after treatment was decreased in 12 cases .Among 36 cases of increased CA242 before treatment ,CA242 after treatment was decreased in 15 cases .The effective rate of analgesic relief in all the cases was 70 .9% (62/86) .Conclusion The integrated therapy of Qingre-huashi herbal formula and HIFU is an effective method for treating advanced pancreatic cancer .
