Correlation of serum hyaluronidase with Ang Ⅱin hepatitis B patients

VernacularTitle:乙型肝炎患者血清HA与AngⅡ的相关性研究
Author: Yong YUAN ; Hong ZHU
Publication Type:Journal Article
Keywords: hepatitis B; hepatic fibrosis; hyaluronidase; angiotensin Ⅱ
From: Chongqing Medicine 2013;(26):3120-3121
CountryChina
Language:Chinese
Abstract: Objective To study on the correlation of hepatic fibrosis with angiotensin Ⅱ (Ang Ⅱ ) in the hepatitis B patients . Methods The electrochemical luminescence and the rate method were adopted to detect hyaluronidase (HA) and Ang Ⅱ levels in 92 cases of acute hepatitis B (acute group) ,108 cases of chronic hepatitis B(chronic group) and 50 healthy people(control group) , and the detected results were performed the correlation analysis .Results Compared with the acute group and the control group ,the HA and Ang Ⅱ levels in the chronic group were increased significantly (P<0 .05) .The HA and Ang Ⅱ levels had statistical differ-ence between the acute group and the control group (P<0 .05) .Further analysis showed that there was a positive correlation be-tween HA and Ang Ⅱ levels(r=0 .629 ,P<0 .05) .Conclusion There the HA level is closely related with the Ang Ⅱ level ,and both of them participate in the process of liver fibrosis ,their levels have the guiding significance in evaluation of severity of liver fi-brosis in the patients with hepatitis B .