Paired basic amino acid cleaving enzyme 4 and tumor
10.3760/cma.j.issn.1673-422X.2013.08.004
- VernacularTitle:偶合基本氨基酸裂解酶4与肿瘤
- Author:
Feifei WANG
;
Lin WANG
;
Liang JIANG
;
Jihong PAN
- Publication Type:Journal Article
- Keywords:
Subtilisin-like proprotein convertases;
Neoplasms;
Gene expression
- From:
Journal of International Oncology
2013;40(8):572-574
- CountryChina
- Language:Chinese
-
Abstract:
Paired basic amino acid cleaving enzyme 4 (PACE4),a subtilisin-like endoprotease,which is thought to play a significant role in tumor occurrence and development.Its over or low expression may lead to enhanced proliferation and invasion of tumor cells,and even increase the malignant degree.The specific regulation according to the roles of PACF4 expression in different tumors may be helpful for tumor treatment and prognosis improvement.
