Progress in research of preparation methods of super paramagnetic iron oxide and the application in cell marking

VernacularTitle:超顺磁性氧化铁的合成及其对细胞标记相关研究进展
Author: Yue GUO ; Xiulan LI ; Yang ZHANG
Publication Type:Journal Article
Keywords: Cell transplantation; Superparamagnetic iron oxide; Tracer technology; Magnetic resonance imaging
From: International Journal of Biomedical Engineering 2013;36(3):172-175
CountryChina
Language:Chinese
Abstract: Cell transplantation has great potentials in repairing damaged tissue.If we want to use the cell transplants to treat diseases that respond poorly to the conventional treatment,or provide better treatments,in vivo dynamic tracking is particularly important.The application of superparamagnetic iron oxide (SPIO) improves a common inconvenience of the current invasive tests including immunohistochemical study or transmission electron microscopy (TEM) study and so on.Researchers has established a variety of preparation methods of the particles,groped the optimal condition of cell marking.SPIO were proved to be feasible and superior in cell tracking in vivo through animal experiments.The results provide the reliable means of using SPIO to track cell in clinical treatments.This review gives a summary of the related study.