Evaluation of comprehensive laparoscopic surgical staging in early-stage ovarian cancer:A meta-analysis
10.3969/j.issn.1000-8179.20131032
- VernacularTitle:腹腔镜在早期卵巢癌全面分期手术中安全性和有效性的Meta分析
- Author:
Yan LU
;
Desheng YAO
;
Jiehua XU
- Publication Type:Journal Article
- Keywords:
laparoscopy;
early-stage ovarian cancer;
staging laparotomy;
meta-analysis
- From:
Chinese Journal of Clinical Oncology
2013;(19):1174-1178
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aimed to assess the efficacy of comprehensive laparoscopic surgical staging in early-stage ovari-an cancer, and provide references for clinical practice and research. Methods: Electronic databases, such as Embase, Medline, Co-chrane Library, CBM, and CNKI, were searched for studies on comprehensive laparoscopic surgical staging versus comprehensive lapa-rotomic surgical staging. Other sources, such as related references, were also retrieved. The literature was screened according to inclu-sion criteria. Data were extracted from the selected references, and the quality of the included studies was assessed. This meta-analysis was performed using RevMan 5.2 software. Results:A total of 11 studies involving 591 cases were selected, of which 235 cases be-longed to the laparoscopy group and 356 belonged to the laparotomy group. No statistically significant differences were observed be-tween groups in age, body mass index, clinical stage, histological type, and histological grade. The laparoscopy group had less intraoper-ative blood loss, earlier general diet intake, less postoperative complications, and lower postoperative recurrence rate than the laparoto-my group. No statistically significant difference was observed between groups in operation time, pelvic lymph node number (apart from pelvic and para-aortic lymph nodes), mortality. Conclusion:The results of this systematic review show that laparoscopic surgical stag-ing of early-stage ovarian cancer demonstrated staging adequacy and accuracy that were similar to those of laparotomic surgical stag-ing. Based on the principle of minimal invasion and radical treatment to tumor, laparoscopy showed more favorable operative outcomes than laparotomy.
