Relationship between non-alcoholic fatty liver disease and chronic metabolic diseases in primary school students

Xiaomin ZHANG; Yanping WAN; Shijun ZHANG; Yiquan ZHOU; Xiaoyan HAN; Hong LIU; Zhiqi CHEN; Liping LU; Jialu WANG; Yin JIANG; Tao TAN

白话标题:小学生非酒精性脂肪性肝病与慢性代谢性疾病的关系
作者: Xiaomin ZHANG ; Yanping WAN ; Shijun ZHANG ; Yiquan ZHOU ; Xiaoyan HAN ; Hong LIU ; Zhiqi CHEN ; Liping LU ; Jialu WANG ; Yin JIANG ; Tao TAN
出版类型:Journal Article
关键字: fatty liver disease; obesity; chronic metabolic disease; child
来源: Journal of Clinical Pediatrics 2013;(9):825-829
国家China
语言:Chinese
摘要: Objectives To investigate the prevalence of non-alcoholic fatty liver (NAFLD) disease and its correlation with chronic metabolic diseases in two primary school students in Shanghai. Methods One thousand ifve hundred and thirty-two 7-11 year-old students from two primary schools were enrolled in Septamber-October 2011. The anthropometric indices, blood pressure, screening for pseudoacanthosis nigricans and liver ultrasonography of all subjects were recorded. Results The overall prevalence of NAFLD, obesity, abdominal obesity, pseudoacanthosis nigricans, high systolic blood pressure and high diastolic blood pressure was 6.5%, 26.7%, 16.3%, 5.1%, 1.7%and 1.9%, respectively. The prevalence of NAFLD and abdomi-nal obesity in students of central urban area was signiifcantly higher than that in suburban area (P<0.01). The binary regression analysis revealed a signiifcant association between NAFLD in students with sex, age, obesity, abdominal obesity, pseudoacan-thosis nigricans and high systolic blood pressure (P<0.05). Conclusions NAFLD has close correlation with chronic metabolic disease in children. It is time to adopt prevention, detection and treatment in NAFLD children with symptoms of chronic meta-bolic diseases.