Parathyroid hormone related peptide and tumor
10.3760/cma.j.issn.1673-422X.2013.07.003
- VernacularTitle:甲状旁腺素相关肽与肿瘤
- Author:
Mingyan YANG
;
Huasheng LIANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Hypercalcemia;
Neoplasm metastasis;
Parathyroid hormone related peptide
- From:
Journal of International Oncology
2013;40(7):489-491
- CountryChina
- Language:Chinese
-
Abstract:
The parathyroid hormone related peptide (PTHrP) participates in regulating calcium and phosphorus metabolism and multiple organ growth,and plays an important role in the processes of malignant tumor bone metastasis and hypercalcemia.Currently,more and more researches have confirmed that PTHrP can be secreted by a variety of types of tumor cells.PTHrP participates in regulating tumor cell proliferation and invasion,and it is closely related to the prognosis of patients,which provides a new target of cancer treatment.