Roles of mitochondria in tumorigenesis
10.3760/cma.j.issn.1673-422X.2013.07.002
- VernacularTitle:线粒体在肿瘤发生中的作用
- Author:
Baihong ZHANG
;
Hongyun YUE
- Publication Type:Journal Article
- Keywords:
Mitochondria;
Neoplasms;
Tumorigenesis
- From:
Journal of International Oncology
2013;40(7):486-488
- CountryChina
- Language:Chinese
-
Abstract:
As semi-autonomous organelles,mitochondria are easily damaged by various factors.Mitochondrial dysfunction such as abnormal oxidative phosphorylation,metabolism alterations,apoptosis prevention,damaged mitophagy,immune escape and deregulated signaling pathway have been hypothesized to be involved in tumorigenesis.Modulated mitochondria may prevent the occurrence of tumors.
