Clinical effect of pseudomonas aeruginosa injection on malignant pleural effusion
10.3969/j.issn.1000-8179.20131234
- VernacularTitle:铜绿假单胞菌注射液在恶性胸腔积液治疗中的疗效观察
- Author:
Feixue SONG
;
Xiaxia PEI
;
Qimei JIN
;
Yan PENG
;
Jun ZHAO
;
Ji XIE
- Publication Type:Journal Article
- Keywords:
pseudomonas aeruginosa injection;
malignant pleural effusion;
cisplatin;
interleukin-2
- From:
Chinese Journal of Clinical Oncology
2013;(18):1127-1129
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of thoracic infusion of pseudomonas aeruginosa injection in malignant pleural effusion. Methods:A total of 90 patients with malignant pleural effusion were randomly divided into treatment group (31 cases),control group A (29 cases) and control group B(30 cases). Treatment group was treated with pseudomonas aeruginosa through intrathoracic infusion. Control group A and B were respectively treated with cisplatin and interleukin-2 through intrathoracic infusion. The clinical efficacy and adverse reaction were compared among the three groups. Results:The total effective rate of treatment group was 80.6%,the total effective rates of the control group A and B were 51.7%and 56.7%respectively.Compared with that of contral groups, the total effective rate of treatment group was higher, and the differences were statistically significant (P<0.05). The incidence of serious side effects and toxicity was lower in treatment group than in control groups. Conclusion:The effect of thoracic infusion of pseudomonas aeruginosa injection for malignant pleural effusion is significant, and the adverse reaction is mild. Thus it is worth to be promoted clinically.
