Optimization of Extraction Process and Inclusion Technology of Volatile Oil in Huangpu Tongqiao Capsules by Orthogonal Design
10.3969/j.issn.1005-5304.2013.08.022
- VernacularTitle:正交设计优选黄蒲通窍胶囊中挥发油的提取及包合工艺
- Author:
Mingsheng ZHANG
;
Liangbing WEI
;
Mei MENG
;
Jiarong GAO
- Publication Type:Journal Article
- Keywords:
Huangpu Tongqiao Capsules;
volatile oil;
orthogonal design;
extraction process;
inclusion process
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2013;(8):61-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction and inclusion process of mixed volatile oil of Rhizoma acori graminei, Fructus alpiniae oxyphyllae and Rhizoma chuanxiong in Huangpu Tongqiao Capsules. Methods With steam distillation method, extraction amount as indicator, the orthogonal experiment was used to optimze the extraction process of volatile oil from three factors such as water amount, soak time and extraction time. With saturated aqueous solution method, co-inclusion compound yield and volatile oil rate as indicators, the orthogonal experiment was used to optimize the inclusion process from three factors such as the proportion of volatile oil and β-CD, inclusion time and inclusion temperature. Results The optimum extraction was:adding eight times amount of water and soak for 2 hours to extract 7 hours. The optimum inclusion process was:the proportion of volatile oil andβ-CD was 1∶10, the inclusion time was 3 hours, the inclusion temperature was 40 ℃. Conclusion Optimal extraction process of oil has higher rate, and the volatile oil inclusion rate of inclusion process was also higher, the process is stable.
