VernacularTitle:代谢组学在“病证效”结合研究中的应用
Author: Yanan SONG ; Yongyu ZHANG ; Shibing SU
Publication Type:Journal Article
Keywords: """Disease-syndrome-efficacy"" integration; metabolomics; application; therapeutic efficiency"
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(4):628-633
CountryChina
Language:Chinese
Abstract: As an important clinical mode, the disease-syndrome-efficacy integration is a development trend of traditional Chinese medicine (TCM) and western medicine combination. The mode combined comprehensive effica-cy evaluation based on disease-syndrome integration is able to highlight advantages of TCM clinical diagnosis and treatment. With the status of disease-syndrome and effects of Chinese herbal medicine treatments, the en-dogenous metabolites and metabolic network of body changed in the systemic level. According to the analysis of these metabolic changes by metabolomic technologies, it is helpful to investigate the essence of disease-syndrome and explain the mechanism of Chinese herbal medicine actions. This review summarized the current applications of metabolomics in the area of disease-syndrome-efficacy integration research . Metabolomics applied in the disease-syndrome-efficacy integration research is helpful to facilitate the development of TCM and western medicine combination .