Application of propofol combined with sub-anesthetic dose of ketamine in delivery analgesia

VernacularTitle:丙泊酚复合亚麻醉剂量氯胺酮在分娩镇痛中的应用
Author: Youxiang ZHANG
Publication Type:Journal Article
Keywords: Propofol; Ketamine; Labor analgesia; Subarachnoid; Epidural
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(15):2337-2339
CountryChina
Language:Chinese
Abstract: Objective To investigate the application of propofol combined with sub-anesthetic dose of ketamine in delivery analgesia.Methods 120 cases were randomly selected and divided into two groups.Control group included 60 cases who were given PCEA and the observation group included 60 cases who were given propofol combined with subanesthetic dose of ketamine before PCEA.Results The VAS scores of two groups had no significant difference(all P ＞0.05).The rate and extent of itching of observation group were significantly lower than control group (P ＜ 0.05).Cesarean section rate and the time of the birth process,the Apgar score of two groups had no significant differ ences (all P ＞ 0.05.Total satisfaction rate of observation group was significantly higher than control group (P ＜ 0.0 5).Awakening time of observation group was (12.1 ± 3.1) min and control group was (13.8 ± 3.5) min.Awakening time of observation group was significantly lower than control group (P ＜ 0.05).Conclusion Propofol combined with subanesthetic dose of ketamine in delivery analgesia can reduce the adverse reactions.It is safe and reliable.