Clinical effect of puerarin and lipoic acid In treatment diabetic peripheral neuropathy

VernacularTitle:葛根素联合硫辛酸治疗糖尿病周围神经病变的临床疗效分析
Author: Shuiqing YU ; Meihua CAO
Publication Type:Journal Article
Keywords: Diabetes; Peripheral neuropathy; Puerarin; Lipoic acid
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(15):2310-2312
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical effect of puerarin and lipoic acid in treatment diabetic peripheral neuropathy.Methods 80 type Ⅱ diabetes patients accompanied with peripheral neuropathy were selected.According to different therapy,they were divided into single drug treatment control group (lipoic acid) and combined treatment group (puerarin + lipoie acid).Total effective rate,MNCV,SNCV,FBG,HbAlc and sorbitol were evaluated after treatment.Results The total effective rate in the treatment group was higher than that in the control group (P ＜ 0.05).Compared with the control group,the recovery rates of MNCV and SNCV were faster in the treatment group(P ＜0.05).And the levels of FBG,HbAlc and sorbitol were significantly lower in the treatment group than in the control group(P ＜ 0.05).Concluslon The clinical effect of puerarin and lipoic acid in treatment diabetic peripheral neuropathy was significant.