Clinical analysis of nifedipine sustained-release tablets in the treatment of hypertension and diabetes mellitus

VernacularTitle:硝苯地平缓释片治疗高血压合并糖尿病临床分析
Author: Qinghai CUI
Publication Type:Journal Article
Keywords: Nifedipine; Hypertension; Diabtes mellitus
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(17):2609-2610
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical effect of nifedipine sustained-release tablets in the treatment of hypertension and diabetes.Methods According to the digtial table,60 patients with hypertension and type 2 diabetes were randomly divided into the observation group and the control group,30 cases in each group.The two groups on the basis of conventional treatment,were given nifedipine sustained-release tablets or losartan.The heart rate,blood pressure,blood urea nitrogen(BUN) and serum creatinine(Scr) level of two groups were compared after 1 treatment courses.The clinical effect was observed.Results In observation group,25 cases with marked effect,4 cases were effective,1 case without effect,the total effective rate was 96.7％.There were 10 cases,15 cases,5 cases in the control group,the total effective rate was 83.3％,there had significant difference between the two groups (x2 =15.43,P ＜0.05).Conclusion Antihypertensive effect of nifedipine sustained-release tablets on hypertension complicated with diabetes mellitus is good,and has no adverse reaction,which is worth promoting in clinical.