Clinical efficacy of captopril combined with amlodipine in hypertension patients of the influence of high noise
- VernacularTitle:卡托普利联合氨氯地平治疗高度噪声影响下的高血压患者的临床疗效
- Author:
Jiancong CHEN
;
Guangyi PENG
;
Lvshun YANG
- Publication Type:Journal Article
- Keywords:
Noise;
Captopril;
Amlodipine;
Hypertension;
Plasma renin activity
- From:
Chinese Journal of Postgraduates of Medicine
2013;36(z1):9-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observed the clinical efficacy of captopril combined with amlodipine in hypertension patients of the influence of high noise.Methods A total of 150 hypertension patients who worked in ＞ 110 dB noise were divided into treatment group 1 (75 cases) and treatment group 2 (75 cases) by random digits table.Patients simply took enalapril in treatment group 1,patients took enalapril combined with amlodipine in treatment group 2.Selected 75 cases common hypertension patients were control group,they took enalapril combined with amlodipine.A year later,compared with three groups of plasma renin activity (PRA) and clinical efficacy.Results The PRA and efficient rate had no significant difference among three groups in half ayear (P ＞0.05).A year later,the PRA and efficient rate in treatment group 2 and treatment group 1 had obvious difference [(1.89 ± 0.37) ng/ (ml· h) vs.(2.40 ± 0.38) ng/ (ml· h),90.67 ％ (68/75) vs.72.00 ％ (54/75)] (P ＜ 0.05 or ＜ 0.01).But compared with control group no significant difference (P ＞0.05).Conclusion The clinical efficacy of captopril combined with amlodipine in hypertension patients is more apparent.
