The significance of combining coagulation with bedside index for severity in acute pancreatitis scores in the severity of acute pancreatitis
10.3760/cma.j.issn.1673-4904.2013.26.006
- VernacularTitle:凝血指标联合急性胰腺炎严重程度床边指数评分对急性胰腺炎严重程度的预测意义
- Author:
Jianqiang HU
- Publication Type:Journal Article
- Keywords:
Pancreatitis;
Coagulation;
Bedside index for severity scores in acute pancreatitis
- From:
Chinese Journal of Postgraduates of Medicine
2013;36(26):15-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the significance of combining coagulation with bedside index for severity in acute pancreatitis (BISAP) scores in evaluation of severity of acute pancreatitis (AP).Methods One hundred and twenty-six patients with AP were diagnosed according to the AP:mild acute pancreatitis (MAP) group of 64 cases,severe acute pancreatitis (SAP) group of 62 cases,and selected 60 healthy persons as control group.AP patients BISAP scores were calculated in 24 h from admission,and the activity of partial thromboplastic time (AFTT),prothrombin time (PT),D-dimer and fibrinogen (FIB) were measured the next morning or after 8 h of fasting peripheral venous blood collected 3 ml.Results There was no significant difference in APTT,PT among three groups (P＞ 0.05).FIB and D-dimer in MAP group and SAP group were significantly higher than those in control group [(4.25 ± 1.01),(5.44 ± 2.19) g/L vs.(3.47 ± 0.49) g/L; (5.08 ± 3.20),(8.65 ± 6.43) mg/L vs.(3.41 ± 2.32) mg/L,P ＜ 0.05],SAP group was significantly higher than that in MAP group(P ＜ 0.05).The positive rate of D-dimer in MAP group was significantly lower than that in SAP group [26.6％(17/64) vs.85.5％ (53/62),P ＜0.01].BISAP scores and combining coagulation with BISAP scores predict the severity of AP AUC were 0.842(0.775-0.889),0.886 (0.839-0.925),there was no statistically significant difference (P ＞0.05).Conclusion The significance of combining coagulation with BISAP scores in the severity of AP is more accurate than only use BISAP scores,and will not increase the clinical application difficulty.
