The clinical effect on hysteromyoma treated with mifepristone of different periods
- VernacularTitle:不同疗程米非司酮治疗子宫肌瘤的疗效评价
- Author:
Huali KE
- Publication Type:Journal Article
- Keywords:
Leiomyoma;
Mifepristone;
Period
- From:
Chinese Journal of Postgraduates of Medicine
2013;36(z1):58-59
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effect and adverse reaction on hysteromyoma patients treated with mifepristone of different periods.Methods Forty-seven patients with conservative treatment were treated with mifepristone of 10 mg/d for 9 months,and 1 period was 3 months.Uterine volume,fibroid volume and hemoglobin (Hb) were detected after each period,and clinical effect and adverse reaction were also observed.Results All patients were completed 3 periods,and clinical symptoms improved.Uterine volume and fibroid volume reduced gradually,and Hb increased gradually during treatment.Uterine volume and fibroid volume reduced by 41.54％ and 46.53％ respectively.All indicators had significant changes at first period and second period,compared with without treatment and first period gradually (P ＜ 0.05).There was no significant difference in adverse reaction among different periods (P ＞ 0.05).Conclusions The clinical effect on hysteromyoma treated with mifepristone of long-period was effective,and adverse reaction did not significantly increase.Long-period treatment with mifepristone provide a conservative treatment for near menopausal hysteromyoma patients.
