The value of procalcitonin in the diagnosis and treatment of infective endocarditis patients
10.3760/cma.j.issn.1671-0282.2013.08.025
- VernacularTitle:降钙素原对感染性心膜炎的诊疗价值
- Author:
Qian ZHANG
;
Jingping ZHANG
- Publication Type:Journal Article
- Keywords:
Procalcitonin;
endocarditis;
C-Reactive Protein;
Staphylococcus aureus;
Diagnosis;
Treatment;
Prognosis;
Operation
- From:
Chinese Journal of Emergency Medicine
2013;22(8):907-911
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of procalcitonin (PCT) in the diagnosis and treatment of infective endocarditis (IE).Methods It was a retrospective study of 20 cases diagnosed as IE with positive culture between June 2010 and June 2012 of First Affiliated Hospital of China Medical University,Department of Infectious Diseases.Results The concentration of C-Reactive Protein (CRP) and PCT in the dead group recorded on the first day and the fifth day in the treatment was significant higher than the survival group.The decreased degree of CRP and PCT concentration after treatment in the dead group was much deeper than the survival group.Moreover,the concentration of CRP and PCT in Staphylococcus aureus IE and negative bacilli IE were significant higher than Streptococcus viridans IE or Enterococcus faecalis IE,which was commonly above 2 μg/ml level.Conclusions Serum procalcitonin,lined with CRP,has the similar significance in the assessment of infective endocarditis severity,however,PCT is slightly better than CRP in assessing prognosis.The concentration of procalcitonin has implications to the strains of IE pathogen,in the mean time,it' s beneficial to guide the early use of antibiotics.
